In Indiana Jones and the Great Circle, The Cloud Atlas Mystery will have Indiana Jones searching for clues at the Nazi weather station in order to crack the code for a locked chest found inside. Locked chests with combinations can be found throughout the game, and will only be able to be unlocked by solving the corresponding puzzle. Typically, this puzzle comes in the form of a cipher, in which the combination has been translated through a code that must be deciphered.

The Cloud Atlas Mystery is located in Gizeh, the third location of the game. In order to begin working on the solution to this mystery, Indy will have to first locate the locked chest in order to search the surrounding area for clues. These clues are usually documents and notes that will provide you with the pieces of the puzzle, which come together to form a concrete solution.