The best cartoon girl duos have ensured that generations of young women fell in love with animation as a medium. What’s more, pairings of female characters also account for some of the most iconic presences in cartoons and animation of all time. While male duos and boy-girl teams in cartoons are common, the world of animation is surprisingly light on pairs of female characters. Girls in cartoons tend to come in trios, groups, or on their own. However, this only ensures that the very best cartoon girl duos stand out.

Whether it’s classic characters from shows like The Flintstones or Scooby-Doo or pairs of heroines from animated movies from powerhouses like Disney or Pixar, each of the best cartoon girl duos brings something unique. They share a range of dynamics, with some being best friends, others sisters, with mother-daughter duos also being present too (and even some granddaughter-grandmother...