Cristin Milioti broke out in a big way last year by playing mob heiress Sofia Falcone in The Penguin, but if you're a fan of Netflix's sci-fi anthology show Black Mirror, you already knew her. In the show's fourth season, she played Nanette, an employee at a video game company who's DNA was borrowed without her consent by her boss (Jesse Plemons), who then used it to create a digital copy of Nanette. In fact, he did that with several coworkers, whom he recast as crew members on the USS Callister. Inside a digital world, he used these people to play out his Star Trek fantasies.

The resulting episode, "USS Callister," was a disturbing, hilarious story about high tech slavery. It was so popular that the upcoming seventh season of Black Mirror will feature a direct sequel episode, something the show has never done before. Milioti will return as Nanette,...