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If there's one thing you need to understand about "Dune," it's that spice is a hell of a drug. The Spice Melange, a substance found only on the planet Arrakis, is a drug so powerful that the entire universe basically revolves around it. Spice can significantly improve someone's health, triple a person's life expectancy, and can give people the ability to predict possible futures.

That last part is the most vital since the humans in the "Dune" universe have long abandoned "thinking machines," so interstellar travel has to be done by humans steering the ship the whole time instead of advanced computers. That's an impossible task, unless the person is heavily dosed up on spice their whole life to the point where they're barely recognizable as human anymore. That's what happened to the Guild Navigators, the spice-addicted space pilots that...