You wouldn’t necessarily think it from the damage he sustains over the course of “Novocaine,” but Nathan Caine ranks among the most risk-averse action heroes the genre has ever seen. That’s because the junior manager of a San Diego bank has a rare disorder known as congenital insensitivity to pain with anhidrosis (or Cipa). One cut could have life-threatening consequences, if not felt and dealt with quickly enough. So it’s kind of a big deal when normally hyper-cautious “Novocaine” (as the other kids called Nathan at school) goes into berserker mode to rescue his crush from bank robbers.

Cipa is a real thing, affecting fewer than one in 100 million people. Technically, that means screenwriter Lars Jacobson is the insensitive one here, not Nathan. If that bothers you, don’t buy a ticket. If it doesn’t, well, Paramount is doing sneak previews on March 8, a week before the film opens wide.