“Rageaholic meets schizophrenic” may not sound like a very enticing hook for a buddy comedy, but that dysfunctional duo proves pretty good company in “Neighborhood Watch.” Duncan Skiles’ first feature since 2018’s darker crime tale “The Clovehitch Killer” recalls shaggier 1970s cinema in its emphasis on quirky character dynamics over suspense, action or plot intricacies. Once again taking a deft low-key approach to a sturdy script (this time by Sean Farley), and armed with engaging lead performances from Jack Quaid and Jeffrey Dean Morgan, Skiles has crafted another accessibly offbeat not-quite-genre item. Rlje is giving a limited theatrical release to “Neighborhood Watch” Friday, along with an on-demand debut, which should reward viewers looking for satisfying if not explosive entertainment.

We first meet thirtyish Simon McNally (Quaid) in a stressful situation — but then, nearly any situation is stressful for him. Interviewing for a Birmingham, Ala. restaurant job, he quickly unravels when...