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An explosion at a "Break-In Party" leads to the discovery of a bomb, and a search ensues for the person who ordered it, before it's too late. Meanwhile, Caine and Calleigh each have personal matters to deal with.

Tobey Hollins is caught by the Miami Police Departement and is sent to prison for murder. Horatio has some doubts about Tobey's guilt, since some evidences clearly identify some one else as the murderer. Horatio and his team now try everything to disprove Tobey's guilt.

A horribly mutilated body of a professor is found lynched on a tree.

A husband and wife are carjacked and she later ends up dead and her husband is wounded. The husband is the oldest brother of a family that owns a very good business.

A man is seen falling from an apartment building, yet the corpse found there is not his but Michael Johnson, a resident, who was deeply wounded by an unidentified round object. First subject is junkie Doug Ramsey, who is arrested by Horatio for probably abseiling to break in and steal the $100,000 heirloom ring of the condo owner, Edward Mathis, who is however found taking it back after its sale, insurance fraud. The wounding object is found, a CD recording kinky sex scenes of missing Donna Scott and reputedly strict criminal judge Isaac Greenhill, whose former court clerk is Mathis, who apparently blackmails him. Ramsay claims police abuse, IAB Sergeant Rick Stetler investigates Horatio, but Ramsay's X-rays... Speculating on a link with the judge's major cases, the team finds Donna's corpse in a strangler's peat swamp dumping ground, with vomit which allows a DNA trace to Mathis, but Horatio now considers him a mere pawn.

A priest, Father Carlos, is found dead in his private office with gunshot wounds in his back. In addition, another case is investigated, in which a woman is found inside a car burned after falling out a cliff.

In the marina, a shark fatally bites Cindy Castiano, attracted by a bleeding earlier shot wound. She worked for P.I. Bruno Gomez to entrap wealthy men. So the suspects include victimized adulterers Carl Purdue, who as ruined and threatened her life, and Matthew Warner, who believes she loved him. Eric tries to pussyfoot after finding MPD detective Frank Tripp's fingerprints and his name on a client list.

A man is found dead, his throat slit, in his office. Meanwhile, Raymond Caine's case is re-opened and eventually solved when Horatio Caine finds more evidence about the murder.

The investigation of the murders of 2 young models hit a sudden stop when the two perpetrators have diplomatic immunity from the US government.

An ex-torturer who once worked for the government of Cuba is found dead, bound to a chair, showing signs of gruesome torture. And a dead man is found near at a bank's ATM.

A case involving the death by shark of a young woman, takes many paths.

Three prisoners break out of prison. One of them is a child molester, previously caught by the CSI team, who is looking for his new victim as the detectives race against time to stop him. Another is out to get revenge against the people who got him convicted, one of whom is detective Calleigh Duquesne.

A man struggles on board a yacht and literally falls dead. On land, a male lap dancer is found dead after a night of partying.

A mother loses sight of her daughter Ruthie for a few seconds only later to find that her little girl is now dead at the hand of a pedophile. As the investigation continues, the detectives realize that they are dealing with a serial pedophile.

A senior woman is found dead in her own blood-splattered apartment in a retirement community. Another case involves a body found inside an abandoned house used for cooking up recreational drugs.

A teen model is found dead near a leech-filled swamp. Another body is found, seemingly burned from the inside.

A plastic surgeon is found dead, hanged in his own apartment. Meanwhile, a husband of his former patient, who died from complications during a routine surgery, is suing the clinic for the death of his wife.

During a routine traffic stop, a cop gets killed and the civilian who drove along with the cop is missing. Horatio and his team find out a 16-year old girl has got something to do with it.

An impending tsunami is the backdrop for a heist gone wrong and bodies keep stacking up as Horatio and his team struggle to pin down the man behind everything.

Horatio and his team investigate a double murder at a concert, but unraveling the mystery becomes difficult when leads take them in two directions: the Mala Noche gang, and a pharmaceutical company.

An environmental lawyer is poisoned with a radioactive isotope and has only one week left to help the CSI team find her murderer.

The body of a man involved in recovering sunken treasure is discovered pinned to the wall of his new cabin cruiser by a spear fired from a spear gun at close range.

A journalist witnesses a homicide and leaves the scene uninjured. The detectives, however, believe that there is more to this suspicious man.

A young girl is kidnapped from her bedroom in the dead of night, and when an arm shows up without the body attached Horatio must determine if it belongs to his victim or a new one.

The murder of a paroled pedophile leads the team to many suspects, one of them at the lab.