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Even as a child, Pablo had a head for business. When he grows up, he begins working with El Alguacil and is introduced to the drug trade.

After his incarceration for theft, Pablo decides to enter the cocaine business by purchasing a farm to ensure drug production.

Pablo and Gonzalo are incarcerated for drug trafficking, while Fabio is forced to accept his sister Patricia's relationship with Pablo.

Using the planes he purchased, Pablo ships drugs to Miami, where Graciela handles distribution. Pablo gives his brother an unforgettable gift.

Pablo builds Hacienda Nápoles. The news of an extradition treaty between Colombia and the United States puts him on high alert.

The search for Irma proves fruitless, and the leaders of the organization meet to discuss the extradition treaty.

Pablo witnesses firsthand the influence politicians can wield, and he ponders going into politics as a means to seize power.

Some of Pablo's partners object his political ambitions. He begins his campaign for Congress, but the Party's leader doesn't want any ties to him.

Both Pablo and Galán see victories in the election, but Pablo is already plotting to get rid of his adversary.

Pablo takes office. Rodrigo Lara is appointed Secretary of Justice and uses the opportunity to make a statement against drug trafficking.

College. Jiménez learns who was behind Rodrigo's assassination and searches for them all over Medellín.

Ministry of Justice Rodrigo Lara Bonilla Is Murder By el cartel de Medellín

The series begins and ends with his dramatic last moments before being shot to death by agents of the Colombian National Police, while escaping from a relative's home, and later flashing back to his childood in Valle de Aburra, Colombia, where Pablo is teased by his cousin, Gonzalo, and older brother, Peluche, on a footbridge crossing a creek, eventually rescued by his mother, who scolds Pablo for crying. His mother's influence on Escobar's life choices is portrayed in the first episode and throughout the series, starting with her admonishment that if he is going to do something bad, he had better do it really well, after he is frustrated while trying to cheat on a test and starting a class rebellion to avoid the consequences. As he and Gonzalo became older, they began their lives of organized crime, becoming bodyguards to a well known smuggler and eventually his partners, after successfully standing off with police in what would become Escobar's trademark "Plata o Plomo" approach to dealing with law enforcement -- "accept our bribe or prepare for a shootout with us." After robbing a bank and being turned in by one of their neighbors, Pablo and his cousin start their careers as murderers by killing him. Thereafter, the series follows Pablo's adventures and misadventures in organized crime and eventually cocaine smuggling, building an empire of wealthy criminals who contest power, often violently, with the Colombian state, eventually leading to murders of prominent politicians, policemen, business associates, friends, lovers, and eventually common citizens. The plot focuses on Escobar's contradictory drives to be a good husband; a decent, upstanding, Colombian citizen; a left-wing politician; a supporter of the poor; and a wealthy, powerful "bandido" (an endearing term for criminal, like "rascal"), all while seeking ever more political power, wealth, and sexual exploits.