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1-199 of 199
- Caroline shares news that forces Dr. Charles to make a serious decision about their relationship. Maggie meets her sister's new boyfriend but danger may lie ahead. Dr. Rhodes experiences a huge loss. Dr. Choi and April face an unexpected challenge.
- Dr. Charles and Caroline set some major plans; Ava fights to keep her relationship with Connor. Agent Lee informs Will of news that may put his life in danger.
- Will and Natalie battle for their lives after a car accident. An investigation is launched following the suspicious death of Cornelius Rhodes. Maggie receives life-changing news. Dr. Charles cuts his honeymoon short to tend to a patient.
- Dr. Choi and Dr. Marcel don't see eye to eye over the treatment of a patient's chronic pain. Rumors circulate about Maggie. Dr. Manning works to help a young boy, but she is challenged by his parents, who believe in only using holistic remedies.
- Maggie gets unsettling news about a new friend and breaks the law to support him; one of the doctors from the Med family is rushed into emergency surgery after a violent assault; a social media influencer lets his users vote on medical advice.
- An entire apartment complex is forced into quarantine when cases of the deadly virus turns into an epidemic. P.D. chases a lead that could point to a case of bio-terrorism and Will gets dangerously close to the suspect.
- A power outage at Med puts multiple patients at risk and tests the skills of the staff and their enthusiastic med students; Natalie returns following her traumatic brain injury; Ethan and April wonder if a family is in their future.
- Dr. Manning's actions with a recent patient lead to serious repercussions. April and Noah disagree over a patient who is injured after a beating. Dr. Charles is visited by a childhood friend with a surprising revelation.
- Dr. Charles and Dr. Halstead sink their teeth into a bloodthirsty case. Dr. Marcel and Maggie throw a traditional craw-fish boil for the staff. A new relationship blossoms while another is left on rocky ground.
- Dr. Choi and Dr. Charles have difficult decisions to make as a dying man tries to preserve his life with a controversial scientific method. Dr. Marcel and April clash over how to handle a mysterious patient.
- April receives unfortunate news that makes her question her future with Ethan. Dr. Charles and Maggie see tough times on the horizon. Natalie's memory from the accident starts to return.
- A a former patient of Dr. Halstead's resurfaces. Upon Ethan's return, April deals with telling the truth or keeping her secret. Dr. Charles deals with the death of his wife.
- After a major accident at O'Hare, the E.D. is concerned one of their own is in mortal danger. Will's proposal for a safe injection site goes to the board for consideration. Natalie and Goodwin become concerned for Gwen.
- The team deals with the aftermath of a school bus crash. Dr. Charles worries Dr. Halstead is putting his medical license in jeopardy. Maggie helps a friend in need.
- Two brothers in critical condition are rushed into the hospital by their parents, leaving Dr. Choi, April and Dr. Charles to tend to their care and left to piece together what actually transpired. Dr. Manning becomes suspicious of a new mother entering the E.D. Dr. Halstead's tireless activities at the safe injection site start to take a toll on his work.
- Dr. Manning and Dr. Marcel disagree over an abusive husband. Dr. Halstead struggles with ethics and his decision to work at the safe injection site. Dr. Charles and Elsa reveal a misdiagnosis that may change a family's life.
- Dr. Charles and Dr. Manning treat a patient who is fully invested in pretending to be someone other than himself. Noah begins to doubt his abilities as a doctor. Dr. Marcel and Dr. Choi are faced with a tough ethical decision. Dr. Halstead puts his faith in an addict.
- A convicted murderer's escape hits close to home when several members of the team find themselves in danger. Dr. Charles and Dr. Halstead continue to clash over patient treatment plans. Dr. Choi and April discover the truth about a patient's scam. Maggie finally receives some good news.
- Marking the series milestone 100th episode, Dr. Manning and Dr. Charles assist in a complicated case helping a 4-year old who they quickly learn is no stranger to the ED. Dr. Marcel and Dr. Choi tend to a police officer with a mysterious gunshot wound to the abdomen. Relationships are put to the test as secrets are revealed.
- Dr. Charles and Goodwin fear Dr. Halstead is repeating his past mistakes when a patient with early-onset Alzheimer's is brought into the E.D. Maggie and Ben become concerned when one of Ben's students is admitted. Dr. Manning and Dr. Marcel treat a terminally ill patient and disagree over the best course of action.
- Dr. Charles evaluates a 15-year old who is brought into the E.D. after an apparent fall off an overpass. Will sides with Dr. Asher on a risky treatment plan. Tensions run high between Dr. Choi and Dr. Marcel.
- Dr. Crockett is visited by two New Orleans detectives who have questions about his past. Dr. Choi puts his life in danger to save a child. Dr. Charles gives fatherly advice to his young daughter.
- In the season six premiere, the entire staff at Chicago Med adjusts to the new normal of the pandemic. Dr. Choi, Dr. Lanik and April fight on the front lines. Dr. Halstead and Hannah face a troubling reality. Dr. Charles tries to clear the air with his daughter following recent developments.
- Will Halstead returns to Med to help Goodwin with a secret investigation. Archer and Charles deal with twins who insist on being identical inside and out. Stevie and Dylan treat a young patient with sickle cell anemia.
- In the aftermath of Halstead's apartment fire, Marcel, Choi and Archer work together to try and save the survivors. Charles and Med's new fellows, Cuevas, helps a paranoid patient. Scott makes a life-changing decision.