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    1-19 of 19
    • Natasha Henstridge in Species II (1998)

      1. Species II

      19981h 33mR19Metascore
      4.5 (33K)
      An astronaut gets infected with alien DNA during the first mission on Mars and runs amok on earth. Preston and Laura team up with a peaceful, genetically re-engineered Sil to track the monster down.
    • Black Bullet (2014)

      2. Black Bullet

      2014TV-MATV Series
      6.8 (3.5K)
      A decade after a virus forces people to live in confinement behind barium walls, two childhood friends with superpowers fight to save the human race.
    • Alien Nation (1989)

      3. Alien Nation

      19891h 42mUnratedTV Movie
      6.9 (1.3K)
      A bigoted human policeman in the L.A. of the future and his alien partner learn to live with each other's differences while attempting to solve a drug conspiracy hidden in the subculture of Los Angeles' newest immigrant population: extraterrestrials.
    • Area 51 (2005)

      4. Area 51

      2005MVideo Game
      7.2 (590)
      In a routine mission, Soldier Ethan Cole must survive a degenerative contamination and find out what is behind everything, which includes events and cases about UFO's and non-terrestrial life covered by the government.
    • Artifact (2013)

      5. Artifact

      2013TV Mini Series
      7.7 (62)
      Human's struggle to obtain ancient Artifacts that have been scattered throughout space.
    • Deep Fear (1998)

      6. Deep Fear

      1998Video Game
      7.5 (21)
      A capsule with an ape sent to space decades ago crash lands in the Pacific near a deep-sea research facility. An alien virus begins mutating everyone there. Ex-Navy SEAL John Mayor must save them and the ape might hold the key.
    • Kat Ludley and Kaitlin Okely in Outlook: a Star Trek Fan Production (2022)

      7. Outlook: a Star Trek Fan Production

      202220mShort
      An isolationist planet declares a humanitarian crisis as a virus ravages through its population. Starfleet steps in to help find a cure and instead uncovers a larger conspiracy more deadly than the virus itself.
    • John Billingsley in Star Trek: Enterprise (2001)

      8. Star Trek: Enterprise

      Episode: 

      Affliction

      (2005)
      2001–200543mTV-PGTV Episode
      7.8 (1.7K)
      While Enterprise is visiting Earth, Phlox is abducted by the Klingons and forced to research a cure for a virus destined to wipe out the race. Reed is tapped by a secret agency and ordered to betray Archer. Trip transfers to the Columbia.
    • Connor Trinneer in Star Trek: Enterprise (2001)

      9. Star Trek: Enterprise

      Episode: 

      Divergence

      (2005)
      2001–200543mTV-PGTV Episode
      7.9 (1.7K)
      While Enterprise tries to bring Trip on board to reverse the malicious Klingon modifications, Phlox and Antaak find a cure for the virus that will not please General K'Vagh.
    • Jolene Blalock in Star Trek: Enterprise (2001)

      10. Star Trek: Enterprise

      Episode: 

      Extinction

      (2003)
      2001–200543mTV-PGTV Episode
      6.0 (1.8K)
      Archer, Reed and Sato are transformed into aliens while visiting a planet.
    • Future Imperfect (1990)

      11. Star Trek: The Next Generation

      Episode: 

      Future Imperfect

      (1990)
      1987–199446mTV-PGTV Episode
      7.7 (3.9K)
      Riker awakens sixteen years after an away mission where he contracted a disease which destroyed his memory back to the point of infection - or so he's told.
    • Robert Beltran and Robert Picardo in Star Trek: Voyager (1995)

      12. Star Trek: Voyager

      Episode: 

      Shattered

      (2001)
      1995–200143mTV-PGTV Episode
      8.2 (2.3K)
      Voyager encounters an energy field which leaves each section - and its crew - existing in a different time period.
    • Gillian Anderson and Jeff Gulka in The X-Files (1993)

      13. The X-Files

      Episode: 

      The Beginning

      (1998)
      1993–201845mTV-14TV Episode
      8.1 (3.9K)
      After the events of The X Files (1998) movie, Mulder and Scully's new boss, Kersh, assigns agents Spender and Fowley to work on the X-Files instead of them. Ignoring this, Mulder takes Scully on a hunt for a rampaging alien.
    • Linda Park in Star Trek: Enterprise (2001)

      14. Star Trek: Enterprise

      Episode: 

      Observer Effect

      (2005)
      2001–200543mTV-PGTV Episode
      7.8 (1.8K)
      Noncorporeal aliens inhabit the bodies of Enterprise crew members to study how the crew reacts to a lethal virus infection that has afflicted Trip and Hoshi.
    • Allison Mack and Erica Durance in Smallville (2001)

      15. Smallville

      Episode: 

      Oracle

      (2006)
      2001–201743mTV-PGTV Episode
      8.3 (1.2K)
      Jonathan Kent appears to Clark on his birthday and instructs him that he needs to kill Lionel Luthor because Lionel knows his secret. Meanwhile, Lionel comes clean to Martha about his knowledge of Clark's secret since his possession by Jor-El, and some of his scribblings from his now-telepathic link to Jor-El are revealed to announce that the "Vessel of Zod" is coming. Meanwhile, Lex has another meeting with Milton Fine who tells Lex that he is trying to make a vaccine to protect mankind against an alien virus. When Lana expresses suspicion that Fine is not who he appears to be, Fine reveals his real identity and that "Jonathan Kent" is just another copy of Fine (The Brainiac) sowing seeds of anxiety in Clark.
    • Battle Beneath the Ice (1986)

      16. Centurions

      Episode: 

      Battle Beneath the Ice

      (1986)
      198630mTV-Y7TV Episode
      7.1 (15)
      Max manages to call off Mekko's attack in claiming a meteorite that finally gets secured in Sea lab. The meteorite holds some sort of virus that, when was isolated on a computer chip, takes over every machine, computer and AI unit.
    • Ron Feinberg in Centurions (1986)

      17. Centurions

      Episode: 

      Man or Machine: Part 1

      (1986)
      198630mTV-Y7TV Episode
      7.3 (18)
      During a visit of the rebuild Sealab, the Centurions learn that their team will grow with new recruiters Rex Charger and John Thunder. Dr. Terror finds the star from which the alien computer virus came that destroyed Sealab.
    • CruxEnigma (2017)

      18. Artifact

      Episode: 

      CruxEnigma

      (2017)
      2013TV Episode
      8.6 (23)
      In a Stroy by Allan Linder, a fallen Astronaut searches the unknown for a way home. What he finds will change the future of humanity forever.
    • Artifact (2013)

      19. Artifact

      Episode: 

      Dissimulation

      (2015)
      2013TV Episode
      8.9 (28)
      A Captain searching for an Artifact on a desolate planet, exposes the truths of his mission.

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