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A retired FBI agent with psychological gifts is assigned to help track down "The Tooth Fairy", a mysterious serial killer. Aiding him is imprisoned forensic psychiatrist Dr. Hannibal "The Cannibal" Lecter.

Former FBI profiler Will Graham returns to service to pursue a deranged serial killer dubbed "the Tooth Fairy" by the media.

Modern society's evolution involves stem cells, gene therapy, transplants, and cloning, but also exposes the existence of monsters that hold the key to our race's future.

A forensic psychiatrist must assess a woman accused of a heinous crime who claims she can't remember a thing.

A forensic psychiatrist discovers that all but one of her patient's multiple personalities are murder victims. She will have to find out what's happening before her time is finished.

Jane Halifax is a freelance forensic psychiatrist (f.p.) a psychological super-sleuth immersed in a mire of crime and punishment: Jane is an expert of the human mind.

Forensic psychiatrist Jane Halifax after 20 years returns to her old job helping the police. This time to help find a sniper that's on the loose before it's too late.

A film crew ventures into the forest in search of the mythical 'Jersey Devil'.

A sniper kills young brunettes as the police attempt to grapple with the psychology of the unknown assailant.

A forensic psychatrist of the Police Department falls for a fatal attraction that threatens to terminate his marriage, his career and his life.

The gory ax-murder of one mousy, suburban Texas housewife by another is nearly as shocking as the excuse offered by the bespectacled defendant's attorney: self-defense. Could it be so?

Forensic psychiatrist Fokke Augustinus makes an unexpected career change when he inherits his father's mansion in Groningen where he becomes involved with a criminal organization with a marijuana plantation on his father's land.

Members of a sunken prison ship take refuge at an old lighthouse, unaware one of their most notorious criminals has taken shelter there as well.

A child is missing and a woman is accused of her murder and that of four other children. A forensic psychiatrist is charged with finding out the truth.

An attractive young woman falls in love with a colleague of Forensic Psychologist Jane Halifax, but is found murdered soon afterwards.

In the annals of crime, perhaps no name evokes terror more than that Jack the Ripper. Although this anonymous killer committed his gruesome murders more than a century ago, his name lives on. This program goes to England to investigate the murder of five women, which took place in 1888 and have gripped the collective psyche ever since. Most frightening of all is the fact that murderer was never caught, or even identified. Criminologists present their theories on the identity of the infamous killer. Never-before-released photographs graphically display the vicious work of Jack the Ripper's knife.

Boyd and the team track down murdered police officer Debbie's married lover, but he denies killing her. Meanwhile, stalker Christopher Redford is ready to confess to the murder, but Grace is not convinced he's the guilty man.

How do we get close to a killer the police haven't been able to identify for over 100 years? With the help of renowned British crime historians and authors applying modern techniques, "Mystery Files" unearths new evidence to eliminate an age-old suspect, and to discover a new, likely candidate who was right under the policemen's nose.

The head of the FBI Behavioral Science unit, Jack Crawford, calls on profiler Will Graham to assist them catch a serial killer. The killer has now kidnapped eight women, all similar in appearance and always on a Friday. His most recent victim is Elise Nichols. Graham has been teaching at the FBI academy and isn't too keen on going out into the field. He is particularly empathetic and has a tendency to get far too involved in these types of cases. Crawford arranges for a well-known psychiatrist, Hannibal Lecter, to work with him and ease the stress. It seems Lecter has his own plans for Will.

Beth LeBeau is found murdered, having drowned in her own blood as a result of her face being cut into a Glasgow smile. Graham's mental state continues to sharply decline; he loses hours at a time and when a vivid hallucination causes Graham to contaminate the crime scene, Lecter refers him to a neurologist, an old residency colleague, Dr. Sutcliffe.

Dr. Abel Gideon escapes from custody and begins targeting the psychiatrists who attempted to treat him, displaying their bodies with a Colombian necktie. While Alana Bloom is put under protective custody, Gideon kidnaps Dr. Frederick Chilton and lures Freddie Lounds into a trap, forcing her to write an article about him. Meanwhile, Graham's undiagnosed Encephalitis drives his temperature up, causing severe hallucinations.

Following an offhand comment by Graham, a comb left in the chamber of Georgia Madchen, who accidentally sparks a fire inside her hyperbaric chamber and is burned to death. Angered, Graham deduces that several recent murders were all the work of a copycat patterning after recent serial murders, and that Georgia was killed because she may have remembered the face of whoever had killed Dr. Sutcliffe.

Following his strange trip to Minnesota, Graham is taken into custody by Crawford for the probable murder of Abigail Hobbs. They find her severed ear in his kitchen sink and her blood under his fingernails. Alana is left devastated by the arrest and is determined to find the cause of Graham's dementia, despite Crawford's insistence that there is no underlying cause. She has him draw a clock when he tells her that Dr. Lecter had him perform a similar test, and the results solidify her belief that there is a physical explanation for Graham's instability.

Will and Jack hunt a killer who is burying his victims alive, so they will become fertilizer for his garden of fungus. While the tabloid journalist Freddie sets targets in on Will.

Determined to give Abigail closure, Will and Hannibal take Abigail back to the scene of her father's crimes. But things take a turn for the worse when the copycat killer strikes again.