A young lady doctor causes all the trouble in Alkali Flats. Up to this time the town had never awakened. Then Louise arrived. There was just two hotels in town, one owned by a widow and the other by the mother of Universal Ike, Jr. Louise set out for the widow's hotel. But before she arrived her coming was heralded and every cowboy in the town had engaged a room there. When she went to register every room in the place was taken. So she went to Ike's hotel, engaged a room and hung out her shingle. Young Ike was the first who became ill. Louise was called. But no sooner did Ike become ill than every other man in the town was overtaken with one kind of sickness or another. Louise did her best to tenderly care for each of them. Then the village housewife began to scent something wrong. They went to the hotel in a body. They called in a horse doctor. No horse doctor ever ruined so much romance in so short a time. Louise and the veterinary eloped together.
—Moving Picture World synopsis