- Severe
- Stimpy has sex with a duck to the point where an egg comes out of his anus.
- Ren sodomizes a frog with a stick of dynamite. The frog's anus is shown.
- One episode features plenty of female nudity, and other episodes have nudity but not as much. The show hints that Ren and Stimpy are gay and there is an episode where Stimpy is pregnant. (he is actually constipated)
- Very frequent innuendo.
- Ren and Stimpy often use the phrase "you're the pitcher, I'm the catcher", referencing gay sex. The episode also ends with Ren and Stimpy having sex although it's not seen, but you see the sheets moving.