Guybrush Threepwood (voice)
Inn Keeper / Antique Dealer / Gambler (voice) (as Dave Boat)
LeChuck (voice)
Elaine Marley (voice)
Kate Capsize / Guybrush's Mom / Fairy / Windy (voice)
'Classic' Chester (voice)
Narrator / Bruno / Fred / Larry / Voodoo Priest (voice)
Chester / Crutch / Fin / Rich (voice)
Governor Phatt / Bart / Parrot / Rat (voice)
Voodoo Lady (voice) (as Leilani Jones Wilmore)
Librarian / Kiosk Guard
Bar Keeper / Sentry / Clown / Costumer (voice)
Stan the Salesman / Grillcook / Moose (voice)
Wally the Cartographer / Captain Rum / Filbert the Gardener (voice)
Herman Toothrot / Potman / Frank / Greg (voice)