In a flashback, Vanessa meets The Cut-Wife, who quickly realizes the extent of Vanessa's powers and warns her of the danger that lies ahead - and the evil that pursues her.
Over the course of four harrowing weeks, Sir Malcolm, Ethan, Dr. Frankenstein and Sembene do everything they can to save Vanessa from what's within her.
With Ethan, Sir Malcolm and Dr. Frankenstein now scattered around the world facing their own demons, a shattered and despondent Vanessa seeks the help of Dr. Seward to battle a new evil.
After a vision of the Grand Guignol, Vanessa, Sir Malcolm, Ethan, Dr. Frankenstein and Sembene explore an empty theater - only to be confronted by their worst nightmares.