"Take a Bite Out of Crime" was the tag line for McGruff the Crime Dog.
Angela makes mention at the end of the episode about the movie The Usual Suspects. The actor Chazz Palminteri played Angela's husband and played Dave in The Usual Suspects.
Jane refers to "McGruff" as "Teen Wolf." Two main cast members of the television reboot of Teen Wolf guest-starred on early episodes of Rizzoli and Isles, both as acquaintances of the victim who later turned out to be involved in the circumstances that led to the murder--Crystal Reed as Natalie in episode 1x4, "She Works Hard For the Money," and Arden Cho as Lee in episode 2x8, "My Own Worst Enemy." Both actresses joined the cast of Teen Wolf some time after appearing in this show and played love interests of the titular teen wolf.