One of the riskiest things an actor can do when they're starring on a hit TV show is to leave that show. It's not always the case, partially depending on the series in question, but when some TV actors have attempted to leap from the small screen elsewhere, they only end up squandering their chance. It's true, of course, that you can look at a guy like George Clooney, who had acted steadily for about a decade prior to his prominent role on the NBC hospital drama "ER" and was able to make the jump to the big screen ... eventually. But you can also look at David Caruso, who seemed to jump off the screen in the ABC police drama "NYPD Blue" in its first season, and then chose to leave the show to pursue a film career ... before heading back to the world of TV with the CBS procedural "CSI: Miami.