"Seinfeld" has been parodied or referenced in many other pieces of pop culture, especially other television shows. "It's Always Sunny in Philadelphia" was originally pitched as "'Seinfeld' on crack". "Seinfeld" has also been mentioned on "King of the Hill" and "The Big Bang Theory," and it was the unlikely inspiration for a horror video game.

Have you ever thought about how Jerry, Kramer, Elaine, and George would weather an apocalypse? That concept is exactly what the developers at RareBird Games have been working on since 2021. They have a strange video game that is currently in development and has been rebranded several times. First, it was called "Sinfeld Chronicles," then "Sinfeld Remastered," and now "Sinfeld: Evil Resident," a riff on the "Resident Evil" series. There are homages to other video games, too. The main character wanders through familiar locations from the goofy sitcom, now abandoned after something terrible happened the previous night.