Lionsgate has started production on “Day Drinker,” reteaming Johnny Depp and Penélope Cruz for a fourth time, under the direction of Marc Webb (“Snow White”). Madelyn Cline also stars in the film.

The cast will be rounded out by Manu Ríos, Arón Piper, Juan Diego Botto and Anika Boyle.

“Day Drinker” tells the story of a private yacht bartender (Cline) who encounters a mysterious guest (Depp). They soon find themselves entangled with a criminal figure (Cruz) and connected in ways no one saw coming.

Depp and Cruz previously co-starred in the features “Blow,” “Pirates of the Caribbean: On Stranger Tides” and “Murder on the Orient Express.”

“I’m excited to be starting production with Johnny, Madelyn, Penelope and this incredible cast,” Webb said in a statement. “We’re in a beautiful location with a fantastic crew and a thrilling, ferocious story to tell. This is going to be fun.”

The film,...